Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome
Published: December 1, 2017 | DOI: https://doi.org/10.7860/JCDR/2017/29306.10987
Xiaopeng Yang, Sanming Chai, Xining Xu, Ling Hui, Meiliang Wang
1. Intermediate Physician, Center for Experimental Medicine, Lanzhou General Hospital, Lanzhou Military Command, Lanzhou, Gansu, China.
2. Senior Resident, Reproductive Medicine Center, Gansu Maternal and Child Health Care Hospital, Lanzhou, Gansu, China.
3. Senior Nurse, Center for Experimental Medicine, Lanzhou General Hospital, Lanzhou Military Command, Lanzhou, Gansu, China.
4. Senior Technician, Center for Experimental Medicine, Lanzhou General Hospital, Lanzhou Military Command, Lanzhou, Gansu, China.
5. Senior Technician, Center for Experimental Medicine, Lanzhou General Hospital, Lanzhou Military Command, Lanzhou, Gansu, China.
Correspondence
Mr. Meiliang Wang,
Senior Technician, Center for Experimental Medicine, Lanzhou General Hospital, Lanzhou Military Command,
Lanzhou, Gansu, China.
E-mail: mlwang_2003@yahoo.com
Hantaan Virus (HTNV) infections are mostly associated with fever, haemorrhagic and renal manifestations, known as Haemorrhagic Fever with Renal Syndrome (HFRS). We herein describe three cases with acute HTNV infection, confirming that HTNV infection may cause leukemoid reaction and prominent liver involvement, along with profound thrombocytopenia and mild to severe Acute Kidney Injury (AKI). These cases highlight the need for considering hantavirus testing in cases of thrombocytopenia, extreme leukocytosis, and fever of unknown origin, especially in areas endemic for the infection.
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